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Table 3 Models fit to individual data sets

From: One- and two-locus models for mapping rheumatoid arthritis-susceptibility genes on chromosome 6

Type of analysis and ARPs

No. ARP

Estimate (95% CI) for

  

τ1 (cM)

τ2 (cM)

λ 1

λ 2

NARAC

     

   Full siblings

877

51.8 (48.6–54.9)

84.3 (63.2–105.5)

1.8 (1.4–2.1)

1.2 (1.0–1.4)

   Half siblings

45

18.2 (8.8–27.6)

74.2 (58.8–89.6)

2.3 (0.6–4.0)

1.8 (0.6–3.0)

   Avuncular pairs

84

8.7 (0.0–17.9)

79.8 (57.8–101.8)

1.6 (0.9–2.4)

1.3 (0.2–2.4)

Canada

     

   Full siblings

59

44.1 (29.8–58.4)

156.3 (142.8–169.8)

1.5 (0.5–2.5)

1.7 (0.6–2.8)

France

     

   Full siblings

119

44.9 (33.2–56.7)

NAa

1.7 (0.7–2.6)

NA

UK-Screen 1

     

   Full siblings

237

52.5 (42.8–62.2)

NA

1.5 (1.0–1.9)

NA

  1. aThe two-locus model converged to the one-locus model