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Table 2 Problem 3 empirical power

From: One-stage design is empirically more powerful than two-stage design for family-based genome-wide association studies

 

Powera

SNP index

185

186

191

192

2-stage (n = 10)

0.01

0.66

0.01

0.00

1-stage CSST (n = 9187)

0.04

0.85

0.02

0.01

1-stage CLRT (n = 9187)

0.05

0.83

0.01

0.01

  1. aNominal type I error rate of α = 0.05, using a Bonferroni correction