From: Modeling of PTPN22 and HLA-DRB1 susceptibility to rheumatoid arthritis
Genotype | Co-dominant | Dominant model | Recessive model |
---|---|---|---|
Penetrancea | |||
TT | 1 | 1 | 1 |
TC | 0.54 [0.42–0.75] | 1 | 0.17 [0.13–0.22] |
CC | 0.20 [0.12–0.30] | 0.20 [0.14–0.28] | 0.17 [0.13–0.22] |
Coupling | |||
T | 0.99 [0.54–1] | 0.27 [0.15–0.43] | 0.99 [0.96–1] |
C | 0.07 [0–0.13] | 0.01 [0–0.02] | 0.22 [0.19–0.28] |
-2*log likelihood | -2066.63 | -2073.72 | -2093.58 |
p-value | 0.20 | 0.02 | 1.5 × 10-5 |