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Table 2 Change of LOD scores before and after ENQT transformation averaged over all traits in the groups

From: Normalizing a large number of quantitative traits using empirical normal quantile transformation

  

Average no. SNPs with LOD score above/below:

Methoda

LOD differenceb

above 1

below 1

above 2

below 2

above 3

below 3

Normal traits (81)

vc

0.020

6.3

10.1

4.0

4.6

4.6

2.7

reg

0.022

6.9

9.1

4.6

3.7

2.8

2.6

Non-normal traits (53)

vc

0.107

22.6

71.4

9.2

31.4

8.1

16.8

reg

0.086

31.4

36.4

8.9

13.6

6.1

8.3

High difference in heritability (49)

vc

0.105

25.7

77.9

11.2

35.5

16.5

20.9

reg

0.085

35.7

30.4

9.9

15.6

6.0

7.9

Low difference in heritability (49)

vc

0.043

14.0

22.0

5.5

12.3

6.5

5.0

reg

0.038

12.5

15.3

6.6

5.8

6.5

8.0

High heritability (37)

vc

0.110

28.7

86.1

13.7

47.0

8.3

19.3

rev

0.060

21.9

21.3

8.2

14.2

5.4

6.7

  1. avc and reg stand for variance-components and variance-regression methods, respectively.
  2. bDifference in LOD scores averaged over all markers