Table 1 Significant patterns identified with the pattern-based method
From: Pattern-based mining strategy to detect multi-locus association and gene × environment interaction
Markers in pattern | No. of cases (F/M ratio)a | No. of controls (F/M ratio) | Odds ratio (confidence interval) | Unadjusted p-valueb | Adjusted p-valuec |
|---|---|---|---|---|---|
SNP0177 (allele 1); SNP1131 (allele 1) | 260 (3.9) | 178 (3.3) | 2.06 (1.58–2.68) | 5.04 × 10-8 | 0.00185 |
SNP0177 (allele 1); SNP0610 (genotype 2/2) | 259 (3.7) | 180 (3.5) | 2.0 (1.54–2.61) | 1.57 × 10-7 | 0.00601 |
SNP0177 (allele 1); SNP1130 (allele 2) | 234 (4.3) | 154 (3.6) | 2.06 (1.58–2.69) | 8.03 × 10-8 | 0.00663 |
SNP0177 (allele 1); SNP0615 (genotype 1/1) | 259 (3.7) | 182 (3.4) | 1.97 (1.51–2.55) | 3.08 × 10-7 | 0.01178 |
SNP0177 (allele 1); SNP0603 (genotype 1/1) | 229 (3.7) | 151 (4.2) | 2.02 (1.55–2.65) | 1.49 × 10-7 | 0.01396 |
SNP0177 (allele 1); SNP0604 (genotype 2/2); SNP0605 (genotype 2/2) | 258 (3.8) | 182 (3.4) | 1.95 (1.5–2.54) | 4.42 × 10-7 | 0.01763 |
SNP0177 (allele 1); SNP0609 (genotype 1/1) | 234 (3.6) | 158 (3.7) | 1.98 (1.52–2.58) | 3.41 × 10-7 | 0.02822 |
SNP0177 (allele 1); SNP0606 (genotype 2/2) | 255 (3.9) | 181 (3.4) | 1.92 (1.48–2.49) | 8.68 × 10-7 | 0.03879 |
SNP0177 (allele 1); SNP0672 (allele 2) | 273 (3.5) | 202 (3.5) | 1.86 (1.43–2.42) | 2.33 × 10-6 | 0.04072 |
SNP0177 (allele 1); SNP0608 (genotype 1/1) | 233 (3.6) | 158 (3.7) | 1.96 (1.5–2.56) | 4.91 × 10-7 | 0.04161 |