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Table 1 Type I error rates and power (in percentage) for testing association in the presence of linkage (T1)

From: Joint modeling of linkage and association using affected sib-pair data

   LD group (number of SNPs)
  Significance level (%) r2 = 0 (n = 947) 0 <r2 <= 0.01 (n = 1751) 0.01 <r2 <= 0.1 (n = 304) 0.1 <r2 <= 0.3 (n = 29) 0.3 <r2 <= 0.92 (n = 18)
FBAT-e 5 4.9 29.1 90.4 100 100
  1 1 18.4 85.3 100 100
  0.1 0.1 10.4 77.2 99.9 100
Millstein-b 5 4.9 28.6 90.1 100 100
  1 1 18 84.9 100 100
  0.1 0.1 10.1 76.6 99.9 100
LAMP-LE 5 4.3 22.5 87.8 100 100
  1 0.9 14.3 81.8 100 100
  0.1 0.1 8.2 73.4 99.8 100
TDT 5 5.1 29.9 90.7 100 100
  1 1.1 19.1 85.9 100 100
  0.1 0.1 11 78.1 99.9 100
HST-LE 5 5.2 5.9 21.3 49.9 86.9
  1 1.1 1.4 10.3 41.8 79.5
  0.1 0.1 0.2 4.1 34.1 74.9
HSTDT 5 7.3 29.2 90.2 100 100
  1 1.9 18.6 85.3 100 100
  0.1 0.3 11 77.9 99.8 100