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Figure 1 | BMC Proceedings

Figure 1

From: Identifying single-nucleotide polymorphisms responsible for the linkage signal of rheumatoid arthritis on chromosome 6 by joint modeling of linkage and association

Figure 1

LOD scores for test of linkage and test of association in the presence of linkage. Simulated Replicate 45, representative of most 100 replicates, was randomly selected to illustrate key features. For the tests of linkage (left column), the black solid lines are the LOD scores obtained without the flanking markers, while the blue broken lines are the LOD scores obtained with a grid of flanking markers in the surrounding 30-cM region. For the tests for association in the presence of linkage (right column), the black solid lines are the LOD scores for ASPs+controls, while the red broken lines are the LOD scores for ASPs.

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BMC Proceedings

ISSN: 1753-6561

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