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Table 1 Parameter settings for simulating disease models

From: A logistic mixture model for a family-based association study

Disease modela

f 0 b

f 1 b

f 2 b

p D c

Prevalence

D3

0.010

0.030

0.030

0.300

0.020

D6

0.010

0.060

0.060

0.300

0.036

D9

0.010

0.090

0.090

0.300

0.051

R3

0.010

0.010

0.030

0.300

0.012

R6

0.010

0.010

0.060

0.300

0.015

R9

0.010

0.010

0.090

0.300

0.017

A3

0.010

0.020

0.030

0.300

0.016

A6

0.010

0.035

0.060

0.300

0.025

A9

0.010

0.050

0.090

0.300

0.034

  1. aD, R and A denote (for the minor allele) dominant, recessive, and additive modes of inheritance, respectively.
  2. bf j denotes the penetrance of a genotype with j disease-predisposing alleles.
  3. cDisease-predisposing allele frequency.