Skip to main content

Table 1 Summary of significant associations (p < 0.05) between RA and candidate genes

From: Classification of rheumatoid arthritis status with candidate gene and genome-wide single-nucleotide polymorphisms using random forests

 

Single-gene model

Multiple-gene model

Gene*SNP

Carrier-test

Genotype-test

p-Value

OR (95% CI)

PTPN22*rs2476601

<0.0001

<0.0001

<0.0001

2.43 (1.82, 3.24)

CTLA4*CT60

0.0060

0.0172

0.0115

0.72 (0.56, 0.93)

HAVCR1*5509_5511delCAA

0.0339

0.0640

0.0731

0.80 (0.63, 1.02)

SUM04*rs237025

<0.0001

0.0002

0.1044

1.39 (0.94, 2.04)

MAP3K71P2*rs577001

0.0012

0.0017

0.4527

1.14 (0.80, 1.63)