Two-dimensional linkage analyses of rheumatoid arthritis

BMC Proceedings

Table 1 Non-parametric linkage results on RA, and quantitative linkage analysis on RF and anti-CCP

Chr	Region (cM)	Marker	Position	LOD	Trait(s)	No. of SNPs	LD (r²)
3	151.86–161.25	F45a	155.5	4.90	RF, anti-CCP	8	0.025
5	14.69–23.45	F25a	19.0	1.54	RF	6	0.014
6	30.33–38.32	T39a	34.23	11.13	RA*, RF, anti-CCP	4	0.100
	47.06–67.19	D6S291	49.5	13.95	RA*, RF, anti-CCP	10	0.100
	124.80–133.19	H10a	128.93	1.96	RF	7	0.100
8	3.40–12.29	F36b	8.34	1.71	RF, anti-CCP*	7	0.012
16	39.95–48.71	F10a	43.89	2.06	RA	6	0.014
	95.48–105.28	H3c	100.39	1.53	RA	7	0.014
18	75.58–84.57	H43a	80.41	2.04	RA*, anti-CCP	8	0.200
	110.96–119.98	F12a	115.89	1.62	anti-CCP	7	0.200
19	83.91–91.09	F31a	87.66	1.74	RF*, anti-CCP	5	0.025
20	5.81	F26a	2.13	1.71	anti-CCP	1	NA

In the trait column, where more than two traits are listed, the asterisk (*) marks the trait with the higher LOD score, which is listed in the LOD score column. If no trait is indicated with an asterisk, all had the same LOD score value.

ISSN: 1753-6561