Table 1 Percent power to detect association using IgM as a covariate in TDT vs. OSA-TDT in 250 pedigrees
From: An ordered subset approach to including covariates in the transmission disequilibrium test
No. replicates in which a significant effect was detected | ||||
|---|---|---|---|---|
SNPa | p = 0.05 | p = 0.01 | p = 0.001 | p = 0.0001 |
TDT without OSA | ||||
SNP11_389 | 80 | 64 | 25 | 10 |
SNP11_390 | 4 | 1 | 0 | 0 |
OSA high | ||||
SNP11_389 | 100 | 100 | 100 | 100 |
SNP11_390 | 6 | 2 | 0 | 0 |
OSA low | ||||
SNP11_389 | 87 | 86 | 73 | 60 |
SNP11_390 | 9 | 1 | 0 | 0 |