The role of heritability in mapping expression quantitative trait loci

BMC Proceedings

Table 2 Linkage analysis on each individual pedigree

	Genome-wide maximum LOD score obtained from MERLIN-REGRESS by Pedigree^b
Gene^a	1333	1340	1341	1345	1346	1347	1362	1408	1416	1418	1421	1423	1424	1454
OR6A2	0	0	0.29	0	0.11	0.56	0	0	0.18	0.21	1.33 ^c	0	0.47	0
NDUFB4	0.07	0.36	0	0	0	0.37	0.08	0.04	0.06	0.33	3.08	0	0	1.13
MAP3K6	0.05	1.56	0.13	0	0	0	1.03	0	0.66	0.13	0	0	0.55	0.12
RGS1	0	0.14	2.87	0	0.69	0.29	0.21	0	0	0.86	0	0	0.05	0.14
ARPC5L	0	0.01	3.81	1.14	0.14	0.02	0	0.25	0.19	1.11	0	0	0	0
CHI3L2	1.15	0.49	2.78	4.52	0	2.21	0.03	0.27	2.06	1.95	0.05	0.30	0.79	0
ITGB1BP1	4.75	0.02	0	0.32	2.59	0	0.10	0	0	0.08	0	2.60	0.46	0.22
HLA-DPB1	0.08	0.13	0.07	0	0.77	1.15	1.03	0.30	1.99	0	0.69	0	0.40	1.51
HLA-DQB1	0	0	0.11	1.18	0.22	0	0.11	0.18	0.33	0	0.60	0.79	0.22	0.36
ZP3	0.29	0.8	0.01	0.21	0	0.39	0.14	0.78	4.72	0	0	1.50	3.53	1.82

^a Genes were selected as in Table 1.
^b The same SNP that mapped to the genome-wide maximum LOD score for each gene expression with all 14 pedigrees was used in linkage analysis on each individual pedigree
^c LOD > 1 is shown in bold font.

ISSN: 1753-6561