Co-regulation and multilocus determinants of gene expression in humans

BMC Proceedings

Table 1 Expression traits with linkage to SNPs on Chromosomes 5 and 22

Expression Trait	Trait name	Chr	Location (Mb)	Heritability	LOD score	SNP	Location (Mb)
LRAP	Leukocyte-derived arginine aminopeptidase	5q15	96.2	0.59	4.6	rs1824780 ^a	99.7
					3.4	rs1973172	99.7
					3.1	rs1824777	99.6
					2.8	rs421508	83.3
					2.8	rs1464765	111.6
					2.3	rs1020720	80.5
SAR1B	SAR1 gene homolog B (S. cerevisiae)	5q31.1	133.9	0.45	2.1	rs428538	104
TCOF1	Treacher Collins-Franceschetti syndrome 1	5q32-33	149.7	0.41	2.3	rs984091	66.5
GRK6	G protein-coupled receptor kinase 6	5q35	176.7	0.61	2.8	rs984091	66.5
					2.5	rs334908	34.7
					2.2	rs506056	39.8
DDX17	DEAD (Asp-Gl-Ala-Asp) box polypeptide 17	22q13	37.2	0.59	4.6	rs132404	43.4
					4.1	rs80533	39.4
					3.7	rs141418	32.8
					3.5	rs738733	46.6
					3.3	rs760482	37.5
					3	rs734139	35.9
					2.8	rs728591	46.5
					2.3	rs916336	34.9
					2.2	rs2032474	32
					2	rs713912	42.3

ISSN: 1753-6561