Table 2 Biological properties of the clustered expression phenotypes within the hotspot on chromosome 14
From: Transcription activity hot spot, is it real or an artifact?
Gene | Location | Gene ontology molecular function | Gene ontology biological process |
|---|---|---|---|
DDX24 a | chr14q32.13 | nucleotide binding | RNA metabolism |
FDPS | chr1q22 | transferase activity | cholesterol biosynthesis |
TRAM2 | chr6p12.2 | NA | protein targeting |
AP3B1 | chr5q14.1 | binding | intracellular protein transport |
PDIA3 | chr1q21.1 | protein disulfide isomerase activity | electron transport |
SMARCB1 | chr22q11.23 | protein binding | chromatin remodeling |
CBARA1 | chr10q22.1 | calcium ion binding | defense response |
RAP80 | chr5q35.2 | NA | transcription |
GSTO1 | chr10q25.1 | glutathione transferase activity | metabolism |
IGBP1 | chrXq13.1 | protein phosphatase type 2A regulator activity | response to biotic stimulus |
LSM3 | chr3p25.1 | RNA binding | nuclear mRNA splicing, via spliceosome |
INPP5A | chr10q26.3 | inositol phosphatase activity | cell communication |
SEC13L1 | chr3p25.3 | NA | intracellular protein transport |
TXNDC | chr14q22.1 | electron transporter activity | DNA replication |
RPN2 | chr20q11.23 | transferase activity | protein modification |
ATG5 | chr6q21 | NA | autophagy |
NDUFB2 | chr7q34 | NADH dehydrogenase activity | generation of precursor metabolites and energy |
ZA20D3 | chr15q25.1 | DNA binding | NA |