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Table 2 p-Values of autosomal SNPs on chromosome 8 using (1) Offspring Cohort and (2) Original and Offspring Cohort

From: Testing for genetic association taking into account phenotypic information of relatives

 

(1) Offspring Cohort

(2) Nuclear family

SNP

CAa

MCA

GEE

gMQLSb

CAa

MCA

GEE

gMQLSb

RS17094201

7.76 × 10-5

1.27 × 10-4

4.40 × 10-5

9.80 × 10-5

1.16 × 10-5

2.22 × 10-5

1.23 × 10-5

1.05 × 10-5

RS12549036

1.90 × 10-4

2.96 × 10-4

8.62 × 10-4

2.65 × 10-4

8.75 × 10-5

1.48 × 10-4

2.15 × 10-4

8.46 × 10-5

RS4961118

2.33 × 10-3

3.15 × 10-3

2.86 × 10-3

2.10 × 10-3

1.67 × 10-4

2.71 × 10-4

3.80 × 10-4

9.93 × 10-5

RS6586789

4.92 × 10-3

6.38 × 10-3

5.54 × 10-3

5.01 × 10-3

1.47 × 10-4

2.40 × 10-4

1.91 × 10-4

1.23 × 10-4

RS16920160

2.27 × 10-4

3.49 × 10-4

5.70 × 10-4

7.94 × 10-5

5.93 × 10-4

8.89 × 10-4

7.63 × 10-4

1.63 × 10-4

RS3812476

1.80 × 10-3

2.47 × 10-3

3.16 × 10-3

1.02 × 10-3

4.42 × 10-4

6.75 × 10-4

7.14 × 10-4

1.90 × 10-4

RS11989122

4.15 × 10-3

5.43 × 10-3

4.62 × 10-3

4.11 × 10-3

2.62 × 10-4

4.12 × 10-4

2.88 × 10-4

2.09 × 10-4

RS3107646

1.82 × 10-4

2.83 × 10-4

1.37 × 10-4

3.20 × 10-4

3.97 × 10-4

6.11 × 10-4

3.03 × 10-4

4.60 × 10-4

RS2738079

2.68 × 10-3

3.60 × 10-3

4.27 × 10-3

6.79 × 10-3

2.58 × 10-4

4.08 × 10-4

1.34 × 10-4

8.47 × 10-4

RS6980645

2.49 × 10-4

3.82 × 10-4

7.71 × 10-5

5.05 × 10-4

4.00 × 10-4

6.15 × 10-4

4.10 × 10-4

8.70 × 10-4

  1. aStatistically inappropriate test.
  2. bPhenotypic data of un-genotyped individuals were also included.