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Table 1 Results from the analysis of rheumatoid arthritis data

From: Application of imputation methods to the analysis of rheumatoid arthritis data in genome-wide association studies

 

Number of SNPs

Number of Significant SNPs

Methods

BIMBAM

IMPUTE

TUNA

BIMBAM

IMPUTE

TUNA

Results before significant SNPs on chromosome 6 removed

Typed

499,102

515,049

499,084

469

364(428)a

411(431)a

Untyped

2,052,389

2,030,768

236,672

2,025

1,230

139

Total

2,551,491

2,545,817

735,756

2,494

1,594

550

Results after significant SNPs on chromosome 6 removed

Typed

465,977

480,591

465,961

44

55(79)a

96(105)a

Untyped

1,902,577

1,882,164

217,913

201

43

16

Total

2,368,554

2,362,755

683,874

245

98

112

  1. aFor the number of significant SNPs identified in parentheses, m was set as the number of typed SNPs in the Bonferroni correction