Integration of gene ontology pathways with North American Rheumatoid Arthritis Consortium genome-wide association data via linear modeling

Table 2 Number of genes in common between 8 GO biological processes retained in model for NARAC SNP data^a

Model^b	GO:0009605	GO:0006996	GO:0006968	GO:0030036	GO:0007015	GO:0006508	GO:0009100	GO:0006629
	0.018	-0.015	-0.024	0.035	-0.055	0.013	0.017	-0.008
GO:0009605	283	15	14	9	1	8	1	13
GO:0006996		424	0	97	23	11	1	10
GO:0006968			49	0	0	0	0	1
GO:0030036				97	23	1	0	1
GO:0007015					23	0	0	0
GO:0006508						166	6	6
GO:0009100							76	11
GO:0006629								279

^aRow 2 displays the corresponding pathway effect estimate in selected model
^bGO definitions: GO:0009605, response to external stimulus; GO:0006996, organelle organization and biogenesis; GO:0006968, cellular defense response; GO:0030036, actin cytoskeleton organization and biogenesis GO:0007015, actin filament organization; GO:0006508, proteolysis; GO:0009100, glycoprotein metabolic process; GO:0006629, lipid metabolic process.

ISSN: 1753-6561