Fig. 1 (abstract P-108).

NMR did not detect any compositional change in the media (a). Micromolar levels of components can be detected (aromatic region shown). Cell growth in Mobius® 3 L single-use bioreactors (b) shows no difference with the use of Viresolve® Barrier filtered media and feeds (VB+) as compared to 0.22 μm filtered controls (VB-). Glycan profile (c) shows no change with the use of Viresolve® Barrier filtered media