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Table 2 Mean (SD) significance levels (-log10(p)) for each design for fraction of samples f in stage one and for sample sizes 100, 200 and 300 for each method

From: Marker selection for whole-genome association studies with two-stage designs using dense single-nucleotide polymorphisms

 

100

200

300

f

1 stage

2 stage

2 stage-c

1 stage

2 stage

2 stage-c

1 stage

2 stage

2 stage-c

0.3

 

10.8(± 0.29)

11.0(± 0.30)

 

25.1(± 0.40)

25.3(± 0.41)

 

39.7(± 0.47)

39.9(± 0.49)

0.4

11.6(± 0.30)

10.7(± 0.29)

11.0(± 0.30)

26.1(± 0.40)

25.1(± 0.40)

25.4(± 0.40)

40.8(± 0.47)

39.7(± 0.47)

40.1(± 0.47)

0.5

 

10.8(± 0.30)

11.1(± 0.30)

 

25.2(± 0.40)

25.5(± 0.40)

 

39.7(± 0.47)

40.1(± 0.47)