Skip to main content

Table 1 Type I error rate of various statistics

From: Two-stage analysis strategy for identifying the IgM quantitative trait locus

  

α = 0.05

α = 0.01

π 1

Statistics

Reverse normal

Fisher

Reverse normal

Fisher

1

T 2

0.032

0.032

0.010

0.010

 

Wilcoxon

0.044

0.044

0.010

0.010

0.3

T2, T2 a

0.054

0.072

0.012

0.020

 

Wilcoxon, Wilcoxon

0.050

0.054

0.010

0.014

 

Adaptive 1b

0.050

0.054

0.010

0.014

 

Adaptive 2c

0.056

0.048

0.014

0.01

0.5

T2, T2 a

0.046

0.046

0.008

0.010

 

Wilcoxon, Wilcoxon

0.052

0.048

0.014

0.012

 

Adaptive 1b

0.052

0.048

0.014

0.012

 

Adaptive 2c

0.042

0.032

0.014

0.016

  1. aThe two statistics are those used at the first and second stages, respectively.
  2. bThe prespecified statistic used for the exploratory stage is Wilcoxon.
  3. cThe prespecified statistic used for the exploratory stage is T2.