Table 3 Percent power to detect association using severity as a covariate in TDT vs. OSA-TDT in 1500 pedigrees
From: An ordered subset approach to including covariates in the transmission disequilibrium test
No. replicates in which a significant effect was detected | ||||
|---|---|---|---|---|
SNPa | p = 0.05 | p = 0.01 | p = 0.001 | p = 0.0001 |
TDT without OSA | ||||
SNP9_185 | 2 | 0 | 0 | 0 |
SNP9_186 | 2 | 0 | 0 | 0 |
SNP9_192 | 6 | 2 | 0 | 0 |
SNP9_193 | 4 | 0 | 0 | 0 |
OSA high | ||||
SNP9_185 | 22 | 8 | 2 | 0 |
SNP9_186 | 58 | 36 | 12 | 4 |
SNP9_192 | 20 | 5 | 2 | 0 |
SNP9_193 | 4 | 1 | 0 | 0 |
OSA low | ||||
SNP9_185 | 11 | 2 | 0 | 0 |
SNP9_186 | 33 | 10 | 1 | 0 |
SNP9_192 | 6 | 2 | 1 | 0 |
SNP9_193 | 3 | 1 | 0 | 0 |