Incorporating prior biological information in linkage studies increases power and limits multiple testing

BMC Proceedings

Table 4 Genetic (below diagonal) and environmental (above diagonal) correlations between pairs of selected traits

Traits^a	201387_s_at	201862_s_at	202154_x_at	202499_s_at	203787_at	209034_at	212642_s_at	34689_at
201387_s_at		-0.10	0.05	-0.04	0.14	0.01	-0.18	0.26
201862_s_at	*0.88* ^b		-0.16	*0.27*	0.30	*0.32*	0.12	-0.06
202154_x_at	*0.60*	0.64		*-0.58*	*-0.49*	*-0.46*	*-0.21*	*-0.41*
202499_s_at	-0.36	-0.15	-0.22		*0.49*	*0.61*	*0.24*	*0.57*
203787_at	-0.11	-0.12	-0.02	0.22		*0.50*	-0.03	0.12
209034_at	-0.51	-0.30	*-0.48*	0.76	0.47		*0.22*	*0.10*
212642_s_at	-0.23	-0.26	0.25	*0.85*	-0.01	*0.64*		*0.36*
34689_at	0.07	0.44	0.20	0.28	*-0.62*	0.18	0.35

^aSelected traits had chromosome 9 maximum LOD scores ≥ 1 and LOD – 1 support interval that included position 109
^b Significant correlations in bold italics

ISSN: 1753-6561