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Figure 1 | BMC Proceedings

Figure 1

From: Comparison between single-marker analysis using Merlin and multi-marker analysis using LASSO for Framingham simulated data

Figure 1

Association tests of 4589 SNPs on chromosome 22 for Replicate 1 of the simulated LDL phenotype. A, p-values from single-marker analysis using Merlin; B, entry numbers from multi-marker analysis using LASSO; C, comparison of ranks from Merlin and LASSO (correlation = 0.08). Red dots indicate 1 major causal SNP and 12 polygenic SNPs. Cyan points in A indicate 960 SNPs that were not in any of the first 10,000 models from LASSO.

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BMC Proceedings

ISSN: 1753-6561

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