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Table 1 Rare variant density and values of Tajima’s D across populations

From: Rare variant density across the genome and across populations

Population

Slope

Mean Tajima’s D

 

Estimate

Standard Error

p-value

Nonsynonymous SNPs

Synonymous SNPs

Tuscan

0.576

0.005

3.30 × 10−15 a

−0.097

0.161

CEPH

0.626

0.004

5.90 × 10−3 a

−0.151

0.140

Japanese

0.644

0.005

6.60 × 10−8 a

−0.197

0.090

Han Chinese

0.677

0.004

9.33 × 10−1

−0.296

−0.032

Denver Chinese

0.677

0.004

1.30 × 10−3 a

−0.265

−0.028

Yoruba

0.694

0.003

8.80 × 10−2

−0.461

−0.213

Luhya

0.701

0.003

<2.2 × 10−16 a

−0.444

−0.215

All

0.902

0.002

   
  1. Rare variant to total variant slope estimates and standard errors are given for each population and for all the populations pooled. The populations are ranked according to slope. Equality of slopes for contiguous populations (i.e., Tuscan vs. CEPH, CEPH vs. Japanese, etc.) is tested, and the p-value for each comparison is given. Finally, the mean values of Tajima’s D for each population calculated on the basis of nonsynonymous and synonymous SNPs are given.
  2. a Significant difference between the population and the one immediately below.
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BMC Proceedings

ISSN: 1753-6561

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