Table 4 LOOCV rare SNP results for VEGF pathway with trait in three databases
Trait | Database | Number of rare SNPs | P-value (all SNPs) | One SNP removed at a time | |
|---|---|---|---|---|---|
|  |  |  |  | Number of times P ≤ 1 × 10−4 a | Number of times P > 1 × 10−4 |
Q1 | BioCarta | 95 | 6.81 × 10−14 | 95 | 0 |
|  | Reactome | 53 | 1.77 × 10−15 | 53 | 0 |
|  | KEGG | 66 | 1.83 × 10−7 | 66 | 0 |
Disease | BioCarta | 95 | 4.69 × 10−5 | 90 | 5 |
|  | Reactome | 53 | 4.95 × 10−5 | 47 | 6 |
|  | KEGG | 66 | 2.17 × 10−4 | 1 | 65 |