Pathway-based joint effects analysis of rare genetic variants using Genetic Analysis Workshop 17 exon sequence data

Table 5 Power of rare SNPs in the VEGF pathway

Trait	Database	Number of rare SNPs	Number of causal rare SNPs	P-value^a	Power (%) (true positives)
Q1	BioCarta	95	33	9.34 × 10⁻⁴	9.1 (3)
	Reactome	53	25	5.26 × 10⁻⁴	16.0 (4)
	KEGG	66	11	7.58 × 10⁻⁴	18.2 (2)
Disease	BioCarta	95	5	9.34 × 10⁻⁴	0 (0)
	Reactome	53	0	5.26 × 10⁻⁴	0 (0)
	KEGG	66	7	7.58 × 10⁻⁴	0 (0)

ISSN: 1753-6561