| Causal genes | Total SNPs | Causal SNPs1 | % Variance explained2 | Empirical Power | |||||
---|---|---|---|---|---|---|---|---|---|---|
 |  | Common | Rare3 | Common | Rare | Common | Rare | Collapse all SNPs | Collapse rare SNPs | Best rare4 |
1 | MAP4 | 149 | 739 | 3 | 12 | 0.01456 | 0.06336 | 0.99 | 0.17 | 1.00 |
 | FLNB | 321 | 628 | 1 | 5 | 0.00273 | 0.00007 | 0.69 | 0.03 | 0.20 |
 | ARHGEF3 | 899 | 1303 | 2 | 8 | 0.00001 | 0.00006 | 0.28 | 0.07 | 0.11 |
 | TUSC2 | 1 | 9 | 0 | 0 |  |  | 0.21 | 0.04 |  |
 | ABTB1 | 7 | 41 | 2 | 0 | 0.00132 |  | 0.18 | 0.02 |  |
 | NMNAT3 | 157 | 332 | 3 | 6 | 0.00014 | 0.00017 | 0.15 | 0.00 | 0.09 |
2 | ZBTB38 | 175 | 408 | 5 | 4 | 0.00087 | 0.00003 | 0.09 | 0.15 | 0.14 |
 | DNASE1L3 | 57 | 79 | 4 | 4 | 0.00005 | 0.00026 | 0.01 | 0.34 | 0.08 |
 | LOC152217 | 3 | 4 | 1 | 0 | 0.00001 |  | 0.04 | 0.28 |  |
 | SCAP | 31 | 174 | 0 | 2 |  | 0.00004 | 0.03 | 0.51 | 0.05 |
 | BTD | 72 | 216 | 0 | 8 |  | 0.00011 | 0.03 | 0.08 | 0.07 |
 | FBLN2 | 230 | 452 | 1 | 3 | 0.00002 | 0.00006 | 0.02 | 0.06 | 0.04 |
3 | CXCR6 | 5 | 18 | 0 | 1 | Â | <1.0E-5 | 0.12 | 0.03 | 0.28 |
 | PDCD6IP | 145 | 318 | 2 | 3 | 0.00025 | 0.00003 | 0.04 | 0.14 | 0.15 |
 | SUMF1 | 236 | 502 | 1 | 2 | 0.00008 | <1.0E-5 | 0.03 | 0.06 | 0.16 |
 | SENP5 | 130 | 275 | 0 | 5 |  | 0.00007 | 0.02 | 0.03 | 0.12 |
 | PTPLB | 158 | 329 | 1 | 2 | 0.00002 | 0.00004 | 0.02 | 0.03 | 0.10 |
 | PPP2R3A | 198 | 860 | 1 | 11 | <1.0E-5 | 0.00010 | 0.02 | 0.01 | 0.12 |
4 | SEMA3F | 51 | 83 | 0 | 2 | Â | 0.00001 | 0.05 | 0.03 | 0.05 |
 | TFDP2 | 363 | 852 | 0 | 5 |  | 0.00005 | 0.04 | 0.03 | 0.04 |
 | PAK2 | 294 | 516 | 0 | 0 |  |  | 0.04 | 0.02 |  |
 | B4GALT4 | 90 | 126 | 1 | 0 | 0.00002 |  | 0.01 | 0.00 |  |
Overall power | Â | Â | Â | Â | Â | Â | 0.139 | 0.095 | Â | |
Type I error | Â | Â | Â | Â | Â | Â | 0.071 | 0.057 | Â |