Figure 1From: Two-stage family-based designs for sequencing studiesComparison of 1-stage and 2-stage designs. The proportion of being prioritized and being significantfor all 15 functional variants in the MAP4 gene (sorted by %VAR explained in descending order):QTDTM for the 1-stage procedure using all members; score test for prioritizing the top 100 variants using 2, 4, or 6 randomly selected related members for sequencing and prioritizing). SBPintercepts model only.Back to article page