Figure 1From: Kernel score statistic for dependent dataSimulated SBP associates with gene MAP4. Power estimates of the kernel score statistic with 95% confidence limits over 200 simulated study replicates as function of the significance level. The association between rank-normalized simulated systolic blood pressure and MAP4 was tested, adjusting for age, sex, age × sex interaction, and familial polygenic background. Polymorphic SNP numbers vary between study replicates for very rare SNPs with MAF <1% (range in legend, right panel), but not for MAF 1% to 5% (left panel).Back to article page