Genome-wide QTL and eQTL analyses using Mendel

BMC Proceedings

Table 1 Empirical power for testing trivariate DBP and SBP traits and empirical type I error for testing the univariate Q1, based on simulation data in files SIMPHEN.1–SIMPHEN.200

SNP	MAF	(DBP₁, DBP₂, DBP₃)			(SBP₁, SBP₂, SBP₃)			Q₁
SNP	MAF	β _DBP	%Var	Power	β _SBP	%Var	Power	Size
3-47913455	0.0049	−5.4633	0.0036	0.05 ± 0.02	−8.7001	0.0044	0.06 ± 0.02	0.06 ± 0.02
3-47956424	0.3777	−1.4951	0.0117	0.35 ± 0.03	−2.3810	0.0143	0.42 ± 0.03	0.03 ± 0.01
3-47957741	0.0016	−5.0841	0.0024	0.04 ± 0.01	−8.0964	0.0030	0.06 ± 0.02	0.06 ± 0.02
3-47957996	0.0301	−4.6435	0.0122	0.82 ± 0.03	−7.3946	0.0149	0.89 ± 0.02	0.05 ± 0.01
3-48040283	0.0318	−6.2235	0.0229	0.84 ± 0.03	−9.9107	0.0278	0.89 ± 0.02	0.05 ± 0.01
3-48040284	0.0131	−6.9531	0.0091	0.47 ± 0.04	−11.0726	0.0111	0.56 ± 0.06	0.04 ± 0.01

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