Table 2 Top 15 gene–methylation pairs identified by the W-test in experimental dataa
SNP | CpG | Distance (kb) | Gene | MAF | p Value | |
|---|---|---|---|---|---|---|
1 | rs12288568 | cg13342435 | 1.27 | MPPED2 | 0.003 | 7.49E − 06 |
2 | rs11031153 | cg13342435 | 3.86 | MPPED2 | 0.003 | 7.49E − 06 |
3 | rs16921036 | cg13342435 | 1.35 | MPPED2 | 0.001 | 8.68E − 06 |
4 | rs11237066 | cg13340272 | 4.52 | GUCY2E | 0.120 | 1.57E − 05 |
5 | rs7119411 | cg17432267 | 3.75 | C11orf63 | 0.430 | 1.65E − 05 |
6 | rs11025246 | cg08550026 | 8.63 | NAV2 | 0.395 | 1.78E − 05 |
7 | rs4347345 | cg16454587 | 2.50 | – | 0.016 | 2.78E − 05 |
8 | rs16927166 | cg04054921 | 5.60 | TNNT3 | 0.007 | 3.94E − 05 |
9 | rs2165313 | cg11007153 | 2.43 | B3GAT1 | 0.237 | 4.06E − 05 |
10 | rs11025246 | cg04916810 | 9.60 | NAV2 | 0.395 | 4.86E − 05 |
11 | rs3740996 | cg23217386 | 4.60 | TRIM5;TRIM6-TRIM34;TRIM3 | 0.131 | 5.22E − 05 |
12 | rs16921012 | cg13342435 | 7.99 | MPPED2 | 0.001 | 5.86E − 05 |
13 | rs10895360 | cg03879971 | 5.78 | LOC100128088 | 0.024 | 6.04E − 05 |
14 | rs900865 | cg23454003 | 0.87 | – | 0.464 | 6.17E − 05 |
15 | rs1455650 | cg25744613 | 8.27 | ZBTB16 | 0.155 | 7.04E − 05 |