Study | N | Study design | Supplementation protocols | Outcome |
---|---|---|---|---|
Ostojic et al. [1] | 48 | RCT | GAA (1.2 a, 2.4 b, or 4.8 c gr/d) or placebo d for 6 weeks | Handgrip strength ↑ a, b, c 1 RM Bench press ↑ a, b, c Vertical jump ↔ a, b, c, d Anaerobic power ↔ a, b, c, d Aerobic capacity ↔ a, b, c, d |
Semeredi et al. [2] | 14 | RCCT | 1 gr of GAA and 3 gr of creatine/d a or 4 gr/d of creatine for 4 weeks b | Total creatine ↑ a, b Brain creatine ↑ a, b 1RM Bench press ↑ a, b tHcy (μmol/L) ↔ a VO2max ↔ a, b |
Ostojic et al. [3] | 24 | RCT | GAA (2.4 gr/d) a or placebo b by oral administration for 6 weeks | Serum GAA ↑ a Serum creatine ↑ a Serum creatinine ↑ a Serum tHcy ↑ a Serum AST↔ a, b |
Ostojic et al. [4] | 24 | RCT | 2·4 gr GAA/d a, or 2·4 gr/d of GAA with 1·6 gr/d of betaine hydrochloride, 5 mg/d of vitamin B12, 10 mg/d of vitamin B6, and 600 mg/d of folic acid b | Serum creatine ↑ a, b Serum tHcy ↑ a, ↔ b |
Ostojic et al. [5] | 48 | RCT | GAA (1.2 a, 2.4 b, or 4.8 c gr/d) or placebo (Inulin) d for 6 weeks | Serum GAA ↑ a, b, c Serum creatine ↑ a, b, c Serum creatinine ↑ a, b, c Vitamin B6, B12 ↔ a, b, c, d tHcy (μmol/L) ↔ a, b, d; ↑ c |
Ostojic et al. [6] | n=10 | UINT | 2 gr of GAA and 2 gr of creatine/d for 4 weeks | tHcy (μmol/L) ↑ |